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Myelogenous Tumors Associated with Eosinophilia and Rearrangements of the PDGFRA, PDGFRB, and FGFR1 Genes

Myelogenous Tumors associated with eosinophilia and rearrangements of the PDGFRA, PDGFRB and FGFR1 genes

Myelogenous Tumors Associated with Eosinophilia and Rearrangements of the PDGFRA, PDGFRB, and FGFR1 Genes

A. Conventional Cytogenetic Analysis

  • Bone marrow karyotype
  • Peripheral blood karyotype without stimulation

B. Molecular Cytogenetic Analysis (FISH)

  • Detection of deletion of chromosome 4, del(4q12), FIP1L1/PDGFRA
  • Detection of chromosome 5 rearrangement, (5q33), PDGFRB (CMML)
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