Molecular Analysis of Human Leukocyte Antigens (HLA)
Infertility due to recurrent pregnancy loss can be attributed to immunological factors in up to 40% of cases. One such factor is the presence of shared HLA-DQ histocompatibility antigens between the parents.
Studies have shown that when parents share HLA-DQa antigens, the maternal immune tolerance towards the embryo ranges from minimal to absent, potentially resulting in embryo rejection.
The presence of HLA-DQb antigens is frequently observed in cases of recurrent pregnancy loss.
Sample Type: Peripheral blood
Turnaround Time: 1 week