Classical microbiological methods, such as microorganism cultures and immunological and biochemical identification methods, form the basis of infectious disease diagnosis. Problems such as (a) the identification of certain bacteria, (b) limited sensitivity of methods, (c) diagnosis of infections caused by non-cultivable microorganisms, and (d) bacterial typing have led to the complementary use of modern Molecular Biology techniques.
The most important method is the Polymerase Chain Reaction (PCR), which allows faster and more reliable identification and quantification of the infectious agent from any biological fluid, as well as monitoring the course of the infectious disease.
Molecular Detection of Respiratory Infections
SARS-CoV-2
Influenza virus А/В
SARS-CoV-2 / Influenza A/B
Molecular Detection of Sexually Transmitted Bacteria
Chlamydia C. trachomatis, M. hominis, U. urealyticum, N. gonorrhoeae
Treponema pallidum
Trichomonas vaginalis
Mycoplasma genitalium
Mycoplasma hominis
Ureaplasma species
Gardnerella vaginalis
Candida albicans
Molecular Detection of TORCH Infections
Toxoplasmosis
Syphilis
Varicella-zoster
Parvovirus B19
Rubella
Cytomegalovirus (CMV)
Herpes infections related to congenital anomalies
Most TORCH infections cause mild maternal morbidity but can have serious fetal consequences.
Molecular Detection of Herpesviruses
Cytomegalovirus
Epstein-Barr virus
Varicella-zoster virus
Human Herpesvirus 6
Herpes Simplex Virus HSV-1, HSV-2